Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547048 | 0.94 | CTSL (0.44) | CTSLITGB1ITGA4MAPTACE | |
| SCHEMBL7545083 | 0.94 | P2RX7 (0.40) | CTSLITGB1ITGA4MAPTMMP3 | |
| SCHEMBL7547249 | 0.92 | ANPEP (0.44) | CTSLMAPTMMP3MMP1MMP2 | |
| SCHEMBL7544736 | 0.92 | NPY4R (0.42) | CTSLFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL7538222 | 0.91 | CTSL (0.39) | CTSLFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL7540704 | 0.90 | CTSL (0.39) | CTSLITGB1ITGA4MAPTACE | |
| SCHEMBL7540085 | 0.90 | CTSL (0.42) | CTSLFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL7538913 | 0.89 | CTSL (0.39) | CTSLFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL7540980 | 0.89 | FOLH1 (0.43) | CTSLFOLH1ITGB1ITGA4MAPT | |
| SCHEMBL7540853 | 0.89 | CTSL (0.37) | CTSLFOLH1NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |