Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544678 | 0.93 | CTSL (0.39) | CTSLMEN1KMT2AACEALDH1A1 | |
| SCHEMBL7547048 | 0.91 | CTSL (0.44) | CTSLACEMAPTGAAHPGD | |
| SCHEMBL7541963 | 0.91 | MEN1 (0.42) | CTSLMEN1KMT2AACEMMP1 | |
| SCHEMBL7540855 | 0.90 | CTSL (0.40) | CTSLACEMAPTITGB1ITGA4 | |
| SCHEMBL7545083 | 0.90 | P2RX7 (0.40) | CTSLALDH1A1MAPTITGB1ITGA4 | |
| SCHEMBL7542054 | 0.90 | MEN1 (0.41) | CTSLMEN1KMT2AACEALDH1A1 | |
| SCHEMBL7541145 | 0.90 | CTSL (0.39) | CTSLMEN1KMT2AACEALDH1A1 | |
| SCHEMBL7538819 | 0.89 | CTSL (0.36) | CTSLMEN1KMT2AACEALDH1A1 | |
| SCHEMBL7547249 | 0.89 | ANPEP (0.44) | CTSLMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7538959 | 0.87 | MEN1 (0.39) | CTSLMEN1KMT2AACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |