SCHEMBL7541023

SCHEMBL7541023

CCCS(=O)(=O)Oc1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.53
CA1 P00915 1/20 0.53
CA9 Q16790 1/20 0.53
MMP2 P08253 3/20 0.53
MMP9 P14780 3/20 0.53
MMP14 P50281 2/20 0.53
MMP7 P09237 1/20 0.53
CA12 O43570 2/20 0.50
ENPP1 P22413 2/20 0.48
ENPP3 O14638 1/20 0.48
ENPP2 Q13822 1/20 0.48
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PPARG P37231 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27656352 0.89 CA2 (0.50) CA2CA1CA9MMP2MMP9
SCHEMBL9462619 0.85 ALPL (0.51) CA2CA1CA9MMP2MMP9
SCHEMBL2374919 0.85 ALPL (0.51) CA2CA1CA9MMP2MMP9
SCHEMBL27599573 0.85 ALPL (0.51) CA2CA1CA9MMP2MMP9
SCHEMBL27676484 0.85 CA2 (0.59) CA2CA1CA9MMP2MMP9
SCHEMBL14401514 0.84 ENPP1 (0.48) CA2MMP2MMP9MMP14MMP7
SCHEMBL11599122 0.82 MMP2 (0.51) CA2CA1CA9MMP2MMP9
SCHEMBL28263538 0.82 MMP2 (0.51) CA2MMP2MMP9MMP14MMP7
SCHEMBL27611233 0.82 NQO1 (0.54) CA2CA1CA9MMP2MMP9
SCHEMBL27623176 0.82 CA2 (0.52) CA2CA1CA9MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204636-A1 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES DSM N.V. (NL) 2002-05-15 EP disclosed
WO-2001014327-A1 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES DSM N.V. (NL) 2001-03-01 WO disclosed