Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548719 | 0.83 | ALOX5 (0.68) | ALOX5EPHX2ADORA1DYRK1AMEN1 | |
| SCHEMBL7541316 | 0.78 | ALOX5 (0.78) | ALOX5EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7551697 | 0.74 | ALOX5 (0.66) | ALOX5EPHX2MEN1KMT2ALMNA | |
| SCHEMBL7545428 | 0.74 | EPHX2 (0.62) | ALOX5EPHX2TP53MEN1KMT2A | |
| SCHEMBL7550313 | 0.72 | NPC1 (0.58) | ALOX5EPHX2TP53MEN1KMT2A | |
| SCHEMBL7541747 | 0.71 | EPHX2 (0.54) | ALOX5EPHX2TP53MEN1KMT2A | |
| SCHEMBL7541753 | 0.70 | DYRK1A (0.56) | ALOX5EPHX2DYRK1AMEN1KMT2A | |
| SCHEMBL7541546 | 0.70 | EPHX2 (0.55) | ALOX5EPHX2TP53MEN1KMT2A | |
| SCHEMBL7544243 | 0.70 | RAB9A (0.64) | ALOX5EPHX2TP53ADORA1DYRK1A | |
| SCHEMBL7548867 | 0.70 | EPHX2 (0.81) | ALOX5EPHX2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |