Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548719 | 0.84 | ALOX5 (0.68) | DYRK1AALOX5EPHX2GAAMAPT | |
| SCHEMBL7548790 | 0.80 | ALOX5 (0.59) | DYRK1AALOX5EPHX2MAPTRAB9A | |
| SCHEMBL7544690 | 0.78 | MAPT (0.60) | DYRK1AALOX5EPHX2HDAC6GAA | |
| SCHEMBL5376865 | 0.76 | POLB (0.47) | DYRK1AALOX5EPHX2TRPV1GAA | |
| SCHEMBL5378671 | 0.74 | TRPV1 (0.45) | ALOX5EPHX2TRPV1GAAMAPT | |
| SCHEMBL7551697 | 0.73 | ALOX5 (0.66) | ALOX5EPHX2MAPTRAB9ANPC1 | |
| SCHEMBL9335106 | 0.71 | HDAC6 (0.41) | DYRK1AALOX5EPHX2TRPV1HDAC6 | |
| SCHEMBL7546710 | 0.71 | MAPT (0.57) | DYRK1AALOX5EPHX2PDPK1GAA | |
| SCHEMBL27470121 | 0.71 | DYRK1A (0.52) | DYRK1APDPK1TRPV1HDAC6ALDH1A1 | |
| SCHEMBL7541209 | 0.70 | ALOX5 (0.54) | DYRK1AALOX5EPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |