Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546365 | 0.95 | MMP2 (0.39) | MMP2ITGB1ITGA4MMP1MMP3 | |
| SCHEMBL7546360 | 0.95 | MMP2 (0.39) | MMP2ITGB1ITGA4MMP1MMP3 | |
| SCHEMBL7540807 | 0.94 | ANPEP (0.40) | MMP2ALDH1A1MMP1MMP3CTSL | |
| SCHEMBL7538392 | 0.94 | CTSL (0.38) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7538388 | 0.94 | CTSL (0.38) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7538619 | 0.91 | MMP2 (0.40) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7538623 | 0.91 | MMP2 (0.40) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7540799 | 0.89 | ITGB1 (0.42) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7539472 | 0.88 | MMP2 (0.38) | MMP2ITGB1ITGA4ALDH1A1MMP1 | |
| SCHEMBL7539469 | 0.88 | MMP2 (0.38) | MMP2ITGB1ITGA4ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |