Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542140 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4ANPEPMMP2MMP1 | |
| SCHEMBL7541673 | 0.93 | ANPEP (0.50) | ITGB1ITGA4ANPEPMMP2ALDH1A1 | |
| SCHEMBL7539323 | 0.90 | MEN1 (0.39) | ITGB1ITGA4ANPEPALDH1A1MAPT | |
| SCHEMBL7545162 | 0.90 | ITGB1 (0.45) | ITGB1ITGA4ANPEPMMP2MAPT | |
| SCHEMBL7541227 | 0.89 | MMP2 (0.37) | ITGB1ITGA4ANPEPMMP2ALDH1A1 | |
| SCHEMBL7541030 | 0.88 | MMP3 (0.41) | ITGB1ITGA4MMP2ALDH1A1MAPT | |
| SCHEMBL7545845 | 0.87 | MAPK1 (0.37) | ANPEPALDH1A1MAPTMAPK1FPR2 | |
| SCHEMBL7547298 | 0.86 | ITGB1 (0.42) | ITGB1ITGA4ANPEPMMP2MAPT | |
| SCHEMBL7541044 | 0.86 | ITGB1 (0.42) | ITGB1ITGA4ANPEPMMP2MAPT | |
| SCHEMBL7541160 | 0.85 | ITGB1 (0.44) | ITGB1ITGA4ANPEPMMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |