SCHEMBL7541264

SCHEMBL7541264

CC(=O)Nc1ccc(OCc2nc3cc(C)ccc3s2)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 14/20 0.58
EPHX2 P34913 13/20 0.58
ALOX5AP P20292 1/20 0.52
DYRK1A Q13627 3/20 0.50
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545085 0.92 ALOX5 (0.60) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7551643 0.91 ALOX5 (0.56) ALOX5EPHX2ALOX5APNPC1RAB9A
SCHEMBL7550204 0.90 DYRK1A (0.56) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7548333 0.90 ALOX5 (0.62) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7541360 0.89 ALOX5 (0.57) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7542633 0.88 ALOX5 (0.50) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7544335 0.88 ALOX5 (0.71) ALOX5EPHX2ALOX5APNPC1RAB9A
SCHEMBL7543772 0.86 DYRK1A (0.53) ALOX5EPHX2ALOX5APDYRK1A
SCHEMBL7550272 0.86 ALOX5 (0.53) ALOX5EPHX2ALOX5APNPC1RAB9A
SCHEMBL7543452 0.84 NPC1 (0.58) ALOX5EPHX2ALOX5APDYRK1ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed