Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7541336 | 0.77 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL2628907 | 0.74 | SIGMAR1 (0.50) | KMT2ASIGMAR1 | |
| SCHEMBL27587241 | 0.67 | — | — | |
| SCHEMBL14621784 | 0.64 | KMT2A (0.50) | MEN1KMT2ARCE1 | |
| SCHEMBL9716912 | 0.63 | MEN1 (0.43) | MEN1KMT2ARCE1 | |
| Iodide SCHEMBL11239592 | 0.62 | SMN1; SMN2 (0.42) | MEN1KMT2ARCE1 | |
| SCHEMBL2479431 | 0.61 | — | — | |
| SCHEMBL18774372 | 0.60 | MEN1 (0.44) | MEN1KMT2ARCE1 | |
| SCHEMBL9332695 | 0.56 | MEN1 (0.38) | MEN1KMT2ARCE1 | |
| SCHEMBL9332702 | 0.56 | MEN1 (0.41) | MEN1KMT2ARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211249-A1 | NOVEL THIAZINE OR PYRAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |