SCHEMBL7541497

SCHEMBL7541497

C=Cc1ccccc1-c1ccccc1F

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 9/20 0.46
ALDH1A1 P00352 1/20 0.43
NPC1 O15118 1/20 0.40
TDP1 Q9NUW8 1/20 0.35
NOTUM Q6P988 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132630 0.85 ALDH1A1 (0.55) NFE2L2ALDH1A1NPC1TDP1
SCHEMBL28281823 0.83 ALDH1A1 (0.52) NFE2L2ALDH1A1NPC1TDP1
SCHEMBL7107668 0.83 ALDH1A1 (0.52) NFE2L2ALDH1A1NPC1TDP1
SCHEMBL11672692 0.83 NFE2L2 (0.43) NFE2L2ALDH1A1NPC1
SCHEMBL19154062 0.82 NFE2L2 (0.47) NFE2L2ALDH1A1
SCHEMBL27474376 0.82 ERN1 (0.48) NFE2L2ALDH1A1NPC1GRIN2DGRIN3B
SCHEMBL7086146 0.82 NFE2L2 (0.39) NFE2L2ALDH1A1NPC1TDP1
SCHEMBL50061 0.80
SCHEMBL29906330 0.80
SCHEMBL28943441 0.79 CTSL (0.45) NFE2L2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117855600-A Gel polymer electrolyte and application thereof 广州天赐高新材料股份有限公司 2024-04-09 CN claimed
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US claimed
CN-117855600-A Gel polymer electrolyte and application thereof 广州天赐高新材料股份有限公司 2024-04-09 CN disclosed
EP-1211284-A1 Semi-finished products or moulded materials of improved toughness made from propylene polymers Borealis GmbH (AT) 2002-06-05 EP disclosed
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US disclosed
EP-0884356-A2 Blends of polyolefins and syndiotactic vinyl polymeres PCD Polymere AG (AT) 1998-12-16 EP disclosed