Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538627 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1CYP2C19KMT2ACTSK | |
| SCHEMBL6609062 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1CYP2C19KMT2ACTSK | |
| SCHEMBL7563297 | 0.83 | PSEN1 (0.37) | ALDH1A1POLBKMT2ACTSKLMNA | |
| SCHEMBL6618103 | 0.78 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL7430902 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4768444 | 0.76 | — | — | |
| SCHEMBL6609709 | 0.72 | PSEN1 (0.32) | — | |
| SCHEMBL6609716 | 0.72 | — | — | |
| SCHEMBL4768440 | 0.72 | — | — | |
| SCHEMBL6072578 | 0.70 | EPHX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |