⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255 | 0.72 | — | — | |
| SCHEMBL1080070 | 0.72 | — | — | |
| SCHEMBL10021910 | 0.72 | NPC1 (0.35) | — | |
| SCHEMBL1713536 | 0.67 | — | — | |
| SCHEMBL850564 | 0.67 | — | — | |
| SCHEMBL4926690 | 0.67 | HSD17B10 (0.54) | — | |
| SCHEMBL8994058 | 0.67 | APLNR (0.39) | — | |
| SCHEMBL21869962 | 0.67 | — | — | |
| SCHEMBL17577315 | 0.67 | — | — | |
| SCHEMBL2171192 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56005466-A | — | — | None | — | — | JP | disclosed |
| JP-2004795-A | — | — | None | — | — | JP | disclosed |
| US-12630551-B2 | Endocyclic pyrimidinone compounds, and preparation methods, compositions and use thereof | NEUSCO BIOTECH LIMITED (CN) | 2026-05-19 | — | — | US | disclosed |
| US-20260035375-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2026-02-05 | — | — | US | disclosed |
| US-12459952-B2 | TREM2 modulators | MUNA THERAPEUTICS APS (DK) | 2025-11-04 | — | — | US | disclosed |
| EP-4174070-B1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | NEUSCO BIOTECH LTD (CN) | 2025-10-29 | — | — | EP | disclosed |
| EP-4633739-A1 | COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | Flare Therapeutics, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| US-20250223293-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2025-07-10 | — | — | US | disclosed |
| EP-4545530-A1 | TRICYCLIC GYRASE INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| EP-3044225-B1 | TRICYCLIC GYRASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-12-18 | — | — | EP | disclosed |
| EP-0334149-A2 | Pyrimidinyl thionophosphoric-acid esters | BAYER AG (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0309422-A2 | New amidino tricycle derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |
| EP-0309425-A2 | New heterocyclic derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |
| EP-0123861-B1 | UREUM DERIVATIVES | BAYER AG (DE) | 1988-04-20 | — | — | EP | disclosed |
| EP-0118864-B1 | PYRIMIDINYL DERIVATIVES | BAYER AG (DE) | 1986-05-07 | — | — | EP | disclosed |
| US-4552900-A | INSECTIDIDES, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |
| US-4542126-A | Pesticidally active pyrimidin-5-yl-(thio)phosphoric acid ester-amides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0123861-A2 | Ureum derivatives | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |
| JP-S565466-A | PREPARATION OF 5-METHYLPYRIMIDINE DERIVATIVE | YAMASA SHOYU CO LTD | 1981-01-20 | — | — | JP | disclosed |
| EP-0004644-A2 | Pyrimidin(5)yl-(thiono)(thiol)-phosphoric(phosphonic) acid esters or amides, process for their preparation and their use as insecticides and acaricides | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |