Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.42 |
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541982 | 1.00 | MMP3 (0.42) | MMP3MMP2MMP1CTSLITGB1 | |
| SCHEMBL7545718 | 0.93 | ITGB1 (0.45) | MMP3MMP2MMP1ITGB1ITGA4 | |
| SCHEMBL7541296 | 0.93 | ITGB1 (0.45) | MMP3MMP2MMP1ITGB1ITGA4 | |
| SCHEMBL7541440 | 0.91 | MMP3 (0.45) | MMP3MMP2MMP1CTSLITGB1 | |
| SCHEMBL7547298 | 0.88 | ITGB1 (0.42) | MMP3MMP2MMP1ITGB1ITGA4 | |
| SCHEMBL7541044 | 0.88 | ITGB1 (0.42) | MMP3MMP2MMP1ITGB1ITGA4 | |
| SCHEMBL7544936 | 0.88 | ITGB1 (0.41) | ITGB1ITGA4MAPT | |
| SCHEMBL7544863 | 0.88 | ITGB1 (0.41) | ITGB1ITGA4MAPT | |
| SCHEMBL7569287 | 0.88 | CTSL (0.41) | MMP3MMP2MMP1CTSLITGB1 | |
| SCHEMBL7541133 | 0.87 | MMP2 (0.39) | MMP3MMP2MMP1CTSLITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |