Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | CPA1 | P15085 | 4/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.49 |
| ▸ | YAP1 | P46937 | 3/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541768 | 1.00 | MME (0.49) | MMEACECPA1ACE2YAP1 | |
| SCHEMBL7538549 | 0.93 | YAP1 (0.51) | YAP1PPARGCTSSCTSK | |
| SCHEMBL7538553 | 0.93 | YAP1 (0.51) | YAP1PPARGCTSSCTSK | |
| SCHEMBL7541280 | 0.87 | MME (0.52) | MMEACECPA1ACE2YAP1 | |
| SCHEMBL7541287 | 0.87 | MME (0.52) | MMEACECPA1ACE2YAP1 | |
| SCHEMBL7541284 | 0.87 | MME (0.52) | MMEACECPA1ACE2YAP1 | |
| SCHEMBL7540882 | 0.84 | MME (0.55) | MMEACECPA1ACE2ITGB3 | |
| SCHEMBL7540879 | 0.84 | MME (0.55) | MMEACECPA1ACE2ITGB3 | |
| SCHEMBL7539801 | 0.84 | ITGB3 (0.48) | MMEACECPA1ACE2YAP1 | |
| SCHEMBL7539795 | 0.84 | ITGB3 (0.48) | MMEACECPA1ACE2YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |