Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538553 | 1.00 | YAP1 (0.51) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7541768 | 0.93 | MME (0.49) | YAP1CTSSCTSKPPARG | |
| SCHEMBL7541764 | 0.93 | MME (0.49) | YAP1CTSSCTSKPPARG | |
| SCHEMBL7539252 | 0.87 | ALDH1A1 (0.50) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7539256 | 0.87 | ALDH1A1 (0.50) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7539258 | 0.87 | ALDH1A1 (0.50) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3133288 | 0.84 | CTSS (0.60) | YAP1ALDH1A1MEN1KMT2ACTSS | |
| SCHEMBL7541085 | 0.84 | ALDH1A1 (0.53) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7541086 | 0.84 | ALDH1A1 (0.53) | YAP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7545946 | 0.84 | YAP1 (0.51) | YAP1ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |