Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093917 | 0.90 | DNM1 (0.39) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL7098358 | 0.90 | DNM1 (0.39) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL9705885 | 0.84 | GNAI3 (0.50) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL6825299 | 0.83 | GNAI3 (0.49) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL10382687 | 0.83 | SPHK1 (0.44) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL7095309 | 0.82 | GNAI3 (0.48) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL7093133 | 0.82 | GNAI3 (0.48) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL7497784 | 0.82 | GNAI3 (0.48) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL7092727 | 0.82 | RELA (0.48) | ANPEPERAP2GNAI3GNAO1GNAI1 | |
| SCHEMBL27591629 | 0.82 | RELA (0.48) | ANPEPERAP2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242609-A2 | NOVEL COLLOID SYNTHETIC VECTORS FOR GENE THERAPY | Novartis AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049324-A2 | NOVEL COLLOID SYNTHETIC VECTORS FOR GENE THERAPY | NOVARTIS AG (CH) | 2001-07-12 | — | — | WO | disclosed |