Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820978 | 0.94 | GPR119 (0.46) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL19690249 | 0.89 | TSHR (0.46) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL7831565 | 0.79 | GPR119 (0.54) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL521464 | 0.78 | NR1H2 (0.48) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL3028439 | 0.78 | STS (0.50) | TSHRALOX15ATMTACR1ALDH1A1 | |
| SCHEMBL4293214 | 0.78 | OPRM1 (0.49) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL29892887 | 0.78 | STS (0.50) | TSHRALOX15ATMTACR1ALDH1A1 | |
| SCHEMBL15212259 | 0.77 | RORC (0.48) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL3525203 | 0.77 | TACR1 (0.46) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL1010791 | 0.77 | GPR119 (0.43) | GPR119TSHRALOX15ATMTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240142-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. Carlsson Research AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046145-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2001-06-28 | — | — | WO | disclosed |