Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538187 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL11134832 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL30426244 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL17603652 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL7537992 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL15060955 | 0.93 | MAPT (0.50) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL25118612 | 0.86 | CA1 (0.52) | ALDH1A1MAPTKMT2ACA12CA1 | |
| SCHEMBL7356440 | 0.85 | CA2 (0.47) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL7356445 | 0.83 | CA2 (0.60) | ALDH1A1KMT2AASAH2CA12CA1 | |
| SCHEMBL20468019 | 0.83 | CA2 (0.50) | ALDH1A1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |