SCHEMBL7542003

SCHEMBL7542003

O=Cc1cc(C(=O)c2cc(C(=O)O)cc3ccccc23)cc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
CDC25B P30305 4/20 0.44
GPR35 Q9HC97 2/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
POLB P06746 1/20 0.39
PTGER4 P35408 1/20 0.39
CYP19A1 P11511 1/20 0.39
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267828 0.89 MEN1 (0.48) PTPN1GPR35MEN1KMT2AHSD17B10
SCHEMBL7544129 0.81 ERN1 (0.38) CDC25BGPR35MEN1KMT2AHSD17B10
SCHEMBL29406969 0.78 PTPN1 (0.65) PTPN1CDC25BGPR35MEN1KMT2A
SCHEMBL70654 0.78 PTPN1 (0.65) PTPN1CDC25BGPR35MEN1KMT2A
SCHEMBL7537287 0.77 ALDH1A1 (0.41) MEN1KMT2AHSD17B10KDM4EALDH1A1
Hydrochloric Acid SCHEMBL10337056 0.76 PTPN1 (0.62) PTPN1CDC25BGPR35MEN1KMT2A
Hydrochloric Acid SCHEMBL17667161 0.76 PTPN1 (0.62) PTPN1CDC25BGPR35MEN1KMT2A
SCHEMBL1878835 0.76 PTPN1 (0.62) PTPN1CDC25BGPR35MEN1KMT2A
Water SCHEMBL3833109 0.76 PTPN1 (0.62) PTPN1CDC25BGPR35MEN1KMT2A
SCHEMBL28371598 0.75 ALDH1A1 (0.57) MEN1KMT2AHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 PTPN1 2904/4885CDC25B 398/4885GPR35 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.