SCHEMBL754231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754232	1.00	MAPT (0.42)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL754204	0.82	MAPT (0.42)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL754203	0.82	MAPT (0.42)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL753029	0.81	MAOB (0.47)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL753028	0.81	MAOB (0.47)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL18590767	0.78	LMNA (0.42)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL754258	0.75	MAPT (0.47)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL754257	0.75	MAPT (0.47)	MAPTCYP1A2CYP2C9LMNAMEN1
	SCHEMBL755275	0.71	NR1H4 (0.49)	LMNAMEN1KMT2AMMP13NR1H4
	SCHEMBL755274	0.71	NR1H4 (0.49)	LMNAMEN1KMT2AMMP13NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.