Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055976 | 0.79 | CYP11B1 (0.33) | ALDH1A1LMNACYP11B1CYP11B2TSHR | |
| SCHEMBL61361 | 0.77 | CYP19A1 (0.32) | ALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL7053946 | 0.77 | CYP19A1 (0.32) | ALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL29844183 | 0.77 | CYP19A1 (0.32) | ALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL1452046 | 0.76 | CYP11B1 (0.33) | ALDH1A1CYP11B1CYP11B2SMN1; SMN2TDP1 | |
| SCHEMBL1822867 | 0.75 | CYP19A1 (0.31) | CYP11B1CYP11B2 | |
| Lithium SCHEMBL29644507 | 0.75 | CYP19A1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL4612462 | 0.75 | CYP19A1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL7055450 | 0.75 | CYP11B1 (0.33) | ALDH1A1LMNACYP11B1CYP11B2TSHR | |
| SCHEMBL7052655 | 0.74 | CYP19A1 (0.30) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693497-B1 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | BOREALIS TECH OY (FI) | 2002-06-12 | — | — | EP | disclosed |
| EP-0693497-A2 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | PCD-Polymere Gesellschaft m.b.H. (AT) | 1996-01-24 | — | — | EP | disclosed |