SCHEMBL7055976

SCHEMBL7055976

CC1=Cc2ccccc2C1[Si](C)(C1C(C)=Cc2ccccc21)C1C(C)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
CYP19A1 P11511 1/20 0.33
LMNA P02545 3/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053946 0.89 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1LMNAALDH1A1
SCHEMBL29844183 0.89 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1LMNAALDH1A1
SCHEMBL61361 0.89 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1LMNAALDH1A1
SCHEMBL4612462 0.88 CYP19A1 (0.31) CYP11B1CYP11B2CYP19A1
SCHEMBL1822867 0.88 CYP19A1 (0.31) CYP11B1CYP11B2CYP19A1
Lithium SCHEMBL29644507 0.88 CYP19A1 (0.31) CYP11B1CYP11B2CYP19A1
SCHEMBL7055450 0.87 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1LMNATSHR
Hydrochloric Acid SCHEMBL2970565 0.86 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL7196460 0.86 CYP19A1 (0.30) CYP11B1CYP11B2CYP19A1
SCHEMBL7203782 0.86 CYP19A1 (0.30) CYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed