SCHEMBL61361

SCHEMBL61361

CC1=Cc2ccccc2C1[Si](C)(C)C1C(C)=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29844183 1.00 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL4612462 0.98 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL7196460 0.96 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL2970565 0.96 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL8860745 0.96 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
SCHEMBL1453940 0.91 GPR3 (0.33) LMNA
SCHEMBL7055976 0.89 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL1453690 0.88
SCHEMBL7053946 0.88 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL1822867 0.86 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232256-B1 CONTACTING A CYCLOALKADIENYL COMPOUND, A TRANSITION METAL AMIDE, AN ALUMINOXANE, AND OPTIONALLY A SOLID SUPPORT UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-05-15 US claimed
EP-0933383-A1 Catalyst composition for the polymerization of olefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-08-04 EP claimed
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
US-12275810-B2 Telechelic polyolefins and processes for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-15 US disclosed
US-12180314-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-31 US disclosed
US-12129368-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
EP-0692505-A2 Process for procucing propylene block copolymers MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-17 EP disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed
US-5346925-A Method for producing α-olefin polymers MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1994-09-13 US disclosed
EP-0598543-A2 Method for producing Alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1994-05-25 EP disclosed
EP-0566349-A2 Process for producing alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-10-20 EP disclosed
US-5225501-A Transition metal compound and alumoxane catalyst MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-06 US disclosed
EP-0529908-A1 Catalyst useful for the polymerization of olefin MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-03 EP disclosed
EP-0512741-A1 Process for producing a propylene random copolymer MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12129368-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 CYP19A1 2521/4885CYP11B1 3466/4885CYP11B2 3405/4885
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 CYP19A1 2346/4885CYP11B1 2439/4885CYP11B2 2395/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 CYP19A1 2521/4885CYP11B1 3466/4885CYP11B2 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.