SCHEMBL7053946

SCHEMBL7053946

CC1=Cc2ccccc2C1[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL29644507 0.98 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL7055976 0.89 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL29844183 0.88 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL61361 0.88 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
SCHEMBL4612462 0.86 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL1822867 0.86 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL7055450 0.85 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL2970565 0.84 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL7196460 0.84 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
SCHEMBL7203782 0.84 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631592-B Polyethylene and chlorinated polyethylene thereof 株式会社LG化学 2023-06-02 CN disclosed
CN-113631592-A Polyethylene and chlorinated polyethylene thereof 株式会社LG化学 2021-11-09 CN disclosed
CN-110256622-B Reinforced and toughened syndiotactic polystyrene and preparation method thereof 中国科学院长春应用化学研究所 2021-03-16 CN disclosed
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
CN-1097059-C Method for preparing thermoplastic elastomer BAYER AG (DE) 2002-12-25 CN disclosed
EP-0798306-B1 Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 2002-05-22 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
CN-1065868-C substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 2001-05-16 CN disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed
US-6037427-A UNBRIDGED METALLOCENE CATALYSTS USED IN COMBINATION WITH SUITABLE COCATALYST FOR THE POLYMERIZATION OF OLEFINIC MONOMERS SCHMID CLAUDIA (DE) 2000-03-14 US disclosed
CN-1228790-A Method for producing thermoplastic elastomers BAYER AG (DE) 1999-09-15 CN disclosed
US-5780659-A ADDITION POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1998-07-14 US disclosed
CN-1164535-A Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 1997-11-12 CN disclosed
EP-0798306-A1 Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM COMPANY (US) 1997-10-01 EP disclosed