Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 17/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 16/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.49 |
| ▸ | ITGAL | P20701 | 2/20 | 0.49 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542399 | 1.00 | ITGA4 (0.50) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7545004 | 0.95 | ITGA4 (0.47) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7545015 | 0.95 | ITGA4 (0.47) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7546396 | 0.85 | ITGB1 (0.66) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7539183 | 0.83 | HPGD (0.47) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7539182 | 0.83 | HPGD (0.47) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7542115 | 0.81 | TAAR1 (0.50) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7541262 | 0.81 | TAAR1 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7540693 | 0.81 | TAAR1 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7565630 | 0.80 | ITGA4 (0.49) | ITGA4ITGB1ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |