Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545015 | 1.00 | ITGA4 (0.47) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7542399 | 0.95 | ITGA4 (0.50) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7542393 | 0.95 | ITGA4 (0.50) | ITGA4ITGB1ITGB7ITGB2ICAM1 | |
| SCHEMBL7539183 | 0.88 | HPGD (0.47) | ITGA4ITGB1ITGB7TAS1R3TAS1R1 | |
| SCHEMBL7539182 | 0.88 | HPGD (0.47) | ITGA4ITGB1ITGB7TAS1R3TAS1R1 | |
| SCHEMBL7541796 | 0.83 | PPARA (0.57) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7541805 | 0.83 | PPARA (0.57) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7546396 | 0.81 | ITGB1 (0.66) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7538237 | 0.80 | L3MBTL1 (0.44) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL7538234 | 0.80 | L3MBTL1 (0.44) | ITGB2ICAM1ITGALTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |