Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547447 | 0.80 | LCK (0.56) | — | |
| SCHEMBL6655484 | 0.65 | SLC6A7 (0.62) | HCRTR1HCRTR2ALDH1A1KDM4E | |
| SCHEMBL1671948 | 0.64 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL26986179 | 0.64 | GAA (1.00) | HCRTR1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL2790983 | 0.64 | CHRM4 (0.51) | HCRTR1HCRTR2GAAALDH1A1CHRM4 | |
| SCHEMBL13229571 | 0.64 | CHRM4 (0.51) | HCRTR1HCRTR2GAAALDH1A1CHRM4 | |
| SCHEMBL6674771 | 0.63 | L3MBTL1 (0.59) | HCRTR1HCRTR2ALDH1A1KDM4E | |
| SCHEMBL2897923 | 0.62 | KDM4E (0.77) | HCRTR1GAAALDH1A1KDM4ENPSR1 | |
| SCHEMBL10729724 | 0.62 | KDM4E (0.77) | HCRTR1GAAALDH1A1KDM4ENPSR1 | |
| SCHEMBL6657811 | 0.62 | HCRTR1 (0.59) | HCRTR1HCRTR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194152-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1194152-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6316444-B1 | SRC kinase inhibitor compounds | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2001000214-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |