Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 10/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652771 | 0.91 | ALDH1A1 (0.57) | SLC6A7PKMALDH1A1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL6653359 | 0.90 | ALDH1A1 (0.56) | SLC6A7PKMALDH1A1HPGDTSHR | |
| SCHEMBL6651764 | 0.88 | ALDH1A1 (0.59) | SLC6A7ALDH1A1HPGDPARP1KDM4E | |
| SCHEMBL6653362 | 0.88 | ALDH1A1 (0.54) | SLC6A7ALDH1A1HPGDTSHRPARP1 | |
| SCHEMBL6652154 | 0.88 | L3MBTL1 (0.67) | SLC6A7ALDH1A1HPGDPARP1KDM4E | |
| SCHEMBL6652211 | 0.88 | SLC6A7 (0.62) | SLC6A7ALDH1A1HPGDPARP1KDM4E | |
| Hydrochloric Acid SCHEMBL6656739 | 0.87 | ALDH1A1 (0.58) | SLC6A7ALDH1A1HPGDPARP1KDM4E | |
| SCHEMBL6653885 | 0.87 | ALDH1A1 (0.79) | SLC6A7ALDH1A1HPGDKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6653082 | 0.87 | SLC6A7 (0.61) | SLC6A7ALDH1A1HPGDPARP1KDM4E | |
| SCHEMBL6657811 | 0.87 | HCRTR1 (0.59) | SLC6A7ALDH1A1PARP1KDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202087-C | Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments | ESTEVE LABOR DR (ES) | 2005-05-18 | — | — | CN | claimed |
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| CN-1268124-A | Acyl-piperazinyl-pyrimidine derivatives, their preparation and use as medicaments | ESTEVE LABOR DR (ES) | 2000-09-27 | — | — | CN | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |
| CN-1202087-C | Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments | ESTEVE LABOR DR (ES) | 2005-05-18 | — | — | CN | disclosed |
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | disclosed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | disclosed |
| CN-1268124-A | Acyl-piperazinyl-pyrimidine derivatives, their preparation and use as medicaments | ESTEVE LABOR DR (ES) | 2000-09-27 | — | — | CN | disclosed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | disclosed |