SCHEMBL754297

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755075	0.88	ALDH1A1 (0.33)	ALDH1A1POLBNPSR1HTT
	SCHEMBL752004	0.86	ALDH1A1 (0.40)	ALDH1A1POLBNPSR1HTTLMNA
	SCHEMBL756687	0.86	ALDH1A1 (0.33)	ALDH1A1POLBHTTHPGDMAPT
	SCHEMBL753699	0.86	ALDH1A1 (0.33)	ALDH1A1POLBHTTLMNA
	SCHEMBL752332	0.85	HTT (0.36)	ALDH1A1POLBNPSR1HTTLMNA
	SCHEMBL754197	0.83	POLB (0.32)	ALDH1A1POLBTP53
	SCHEMBL756515	0.82	CYP2C9 (0.36)	ALDH1A1POLBNPSR1HTTLMNA
	SCHEMBL16921567	0.82	HSD17B2 (0.38)	ALDH1A1NPSR1HTTLMNAHPGD
	SCHEMBL2489691	0.80	NPSR1 (0.40)	ALDH1A1POLBNPSR1LMNAHPGD
	SCHEMBL757197	0.79	HTT (0.31)	ALDH1A1POLBNPSR1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.