SCHEMBL757197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754197	0.89	POLB (0.32)	ALDH1A1POLB
	SCHEMBL756515	0.83	CYP2C9 (0.36)	HTTALDH1A1KDM4ELMNARAB9A
	SCHEMBL754297	0.79	ALDH1A1 (0.40)	HTTALDH1A1KDM4ELMNARAB9A
	SCHEMBL753137	0.77	ALDH1A1 (0.31)	ALDH1A1POLB
	SCHEMBL765536	0.77	ALDH1A1 (0.36)	ALDH1A1LMNAPOLBHPGD
	SCHEMBL756687	0.76	ALDH1A1 (0.33)	HTTALDH1A1POLBHPGD
	SCHEMBL755075	0.76	ALDH1A1 (0.33)	HTTALDH1A1POLBNPSR1
	SCHEMBL753699	0.76	ALDH1A1 (0.33)	HTTALDH1A1LMNAPOLB
	SCHEMBL752332	0.76	HTT (0.36)	HTTALDH1A1KDM4ELMNARAB9A
	SCHEMBL753227	0.74	HTT (0.37)	HTTALDH1A1LMNARAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.