SCHEMBL752004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18633315	0.91	POLB (0.39)	ALDH1A1POLBLIPGNPSR1RXFP1
	SCHEMBL752967	0.90	POLB (0.38)	ALDH1A1POLBLIPGNPSR1RXFP1
	SCHEMBL765859	0.90	LIPG (0.37)	ALDH1A1POLBLIPGRXFP1LMNA
	SCHEMBL751187	0.89	ALDH1A1 (0.39)	ALDH1A1POLBLIPGNPSR1RXFP1
	SCHEMBL16921574	0.87	ALDH1A1 (0.34)	ALDH1A1POLBLIPGRXFP1LMNA
	SCHEMBL754297	0.86	ALDH1A1 (0.40)	ALDH1A1POLBNPSR1LMNATSHR
	SCHEMBL751997	0.85	ALDH1A1 (0.33)	ALDH1A1POLBLIPG
	SCHEMBL752899	0.85	LIPG (0.51)	ALDH1A1POLBLIPGLMNATSHR
	SCHEMBL753094	0.85	PDE10A (0.34)	HTT
	SCHEMBL752749	0.84	KCNH2 (0.34)	ALDH1A1POLBLIPGHTTGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.