Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543228 | 1.00 | PTPN1 (0.41) | PTPN1ASAH2CYP2C19TBXAS1HCAR2 | |
| SCHEMBL9423105 | 0.90 | TBXAS1 (0.39) | PTPN1ASAH2CYP2C19TBXAS1HCAR2 | |
| SCHEMBL2549349 | 0.85 | ALDH1A1 (0.50) | PTPN1TBXAS1HCAR2ALDH1A1PPARG | |
| SCHEMBL700036 | 0.85 | ALDH1A1 (0.50) | PTPN1TBXAS1HCAR2ALDH1A1PPARG | |
| SCHEMBL700035 | 0.85 | ALDH1A1 (0.50) | PTPN1TBXAS1HCAR2ALDH1A1PPARG | |
| SCHEMBL2552304 | 0.85 | ALDH1A1 (0.50) | PTPN1TBXAS1HCAR2ALDH1A1PPARG | |
| SCHEMBL2552670 | 0.85 | ALDH1A1 (0.50) | PTPN1TBXAS1HCAR2ALDH1A1PPARG | |
| SCHEMBL9423107 | 0.82 | TBXAS1 (0.36) | PTPN1ASAH2CYP2C19TBXAS1HCAR2 | |
| SCHEMBL28332302 | 0.80 | PTPN1 (0.44) | PTPN1CYP2C19HCAR2EPHX2PPARG | |
| SCHEMBL16831416 | 0.77 | ALDH1A1 (0.43) | PTPN1TBXAS1HCAR2ALDH1A1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |