SCHEMBL700036

SCHEMBL700036

COCCCCCCCCCC=CC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
PTPN1 P18031 2/20 0.45
HCAR2 Q8TDS4 2/20 0.42
TBXAS1 P24557 3/20 0.41
LPAR2 Q9HBW0 3/20 0.41
LPAR3 Q9UBY5 3/20 0.41
LPAR1 Q92633 2/20 0.41
PPARG P37231 2/20 0.40
PPARA Q07869 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700035 1.00 ALDH1A1 (0.50) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL2552304 1.00 ALDH1A1 (0.50) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL2552670 1.00 ALDH1A1 (0.50) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL2549349 1.00 ALDH1A1 (0.50) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL16831416 0.92 ALDH1A1 (0.43) ALDH1A1PTPN1HCAR2TBXAS1LPAR3
SCHEMBL5010354 0.92 ALDH1A1 (0.43) ALDH1A1PTPN1HCAR2TBXAS1LPAR3
SCHEMBL9423105 0.86 TBXAS1 (0.39) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL7543228 0.85 PTPN1 (0.41) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL7543224 0.85 PTPN1 (0.41) ALDH1A1PTPN1HCAR2TBXAS1LPAR2
SCHEMBL4888380 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3269802-A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION Bluebird Bio, Inc. (US) 2018-01-17 EP claimed
EP-2760994-B1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION BLUEBIRD BIO INC (US) 2017-05-31 EP claimed
US-20150216903-A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION BLUEBIRD BIO, INC. (US) 2015-08-06 US claimed
US-20140234278-A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION GENETIX BIOTHERAPEUTICS INC. 2014-08-21 US claimed
EP-2760994-A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION Bluebird Bio, Inc. (US) 2014-08-06 EP claimed
WO-2014026110-A2 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION BLUEBIRD BIO, INC. (US) 2014-02-13 WO claimed
WO-2013049615-A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION BLUEBIRD BIO, INC. (US) 2013-04-04 WO claimed
US-20090285786-A1 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-11-19 US claimed
JP-2009530408-A 2009-08-27 JP claimed
EP-1999255-A2 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH The Children's Medical Center Corporation (US) 2008-12-10 EP claimed
WO-2007112084-A9 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDRENS MEDICAL CENTER (US) 2007-11-22 WO claimed
WO-2007112084-A2 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDREN'S MEDICAL CENTER CORPORATION (US) 2007-10-04 WO claimed
US-20260022403-A1 VCN ENHANCER COMPOSITIONS AND METHODS OF USING THE SAME BLUEBIRD BIO INC (US) 2026-01-22 US disclosed
US-20250290097-A1 COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) 2025-09-18 US disclosed
US-20250134927-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES ORCHARD THERAPEUTICS EUROPE LTD (GB) 2025-05-01 US disclosed
US-12234476-B2 VCN enhancer compositions and methods of using the same BLUEBIRD BIO, INC. (US) 2025-02-25 US disclosed
US-20090285786-A1 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-11-19 US disclosed
EP-1999255-A2 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH The Children's Medical Center Corporation (US) 2008-12-10 EP disclosed
WO-2007112084-A9 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDRENS MEDICAL CENTER (US) 2007-11-22 WO disclosed
WO-2007112084-A2 METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH CHILDREN'S MEDICAL CENTER CORPORATION (US) 2007-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022403-A1 VCN ENHANCER COMPOSITIONS AND METHODS OF USING THE SAME PTGES2, POLN, HPGDS ALDH1A1 1918/4885PTPN1 4736/4885HCAR2 4209/4885
US-20250134927-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES CD4, CD74, HLA-DRB1 ALDH1A1 2029/4885PTPN1 686/4885HCAR2 1150/4885
US-20250290097-A1 COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS PHAX, CD44, HCLS1 ALDH1A1 2544/4885PTPN1 2968/4885HCAR2 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.