Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301607 | 0.94 | GNAI3 (0.46) | GSRGNAI3GNAO1GNAI1MMP2 | |
| SCHEMBL11660913 | 0.94 | GNAI3 (0.46) | GSRGNAI3GNAO1GNAI1MMP2 | |
| SCHEMBL2057401 | 0.93 | GNAI3 (0.44) | GSRGNAI3GNAO1GNAI1MMP2 | |
| SCHEMBL769420 | 0.89 | GNAI3 (0.40) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL288133 | 0.85 | NPY4R (0.39) | GNAI3GNAO1GNAI1DPP7NPY4R | |
| SCHEMBL9237239 | 0.85 | NPY4R (0.39) | GNAI3GNAO1GNAI1DPP7NPY4R | |
| SCHEMBL28712062 | 0.85 | NPY4R (0.39) | GNAI3GNAO1GNAI1DPP7NPY4R | |
| Lysine SCHEMBL7543431 | 0.84 | GSR (0.65) | GSRGNAI3GNAO1GNAI1NOS1 | |
| Lysine SCHEMBL7543435 | 0.84 | GSR (0.65) | GSRGNAI3GNAO1GNAI1NOS1 | |
| SCHEMBL6535302 | 0.84 | GSR (0.45) | GSRGNAI3GNAO1GNAI1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049301-A1 | Short peptides which selectively modulate the activity of serine/threonine kinases | THE CHILDREN'S MEDICAL CENTER CORP. (US) | 2002-04-25 | — | — | US | claimed |
| US-6174993-B1 | DERIVATIVE OF HJ LOOP WHICH IS 5 TO 20 AMINO ACIDS LONG; ANTICARCINOGENIC AGENTS; ANTIINFLAMMATORY AGENTS; ANTIDIABETIC AGENTS; TREATMENT OF OBESITY, AUTOIMMUNE DISORDERS, AND CARDIOVASCULAR DISORDERS | THE CHILDREN'S MEDICAL CENTER CORP. | 2001-01-16 | — | — | US | claimed |
| EP-0983346-A2 | SHORT PEPTIDES WHICH SELECTIVELY MODULATE THE ACTIVITY OF SERINE/THREONINE KINASES | The Children's Medical Center Corporation (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998053050-A2 | SHORT PEPTIDES WHICH SELECTIVELY MODULATE THE ACTIVITY OF SERINE/THREONINE KINASES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-11-26 | — | — | WO | claimed |