Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 5/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL1278093 | 0.93 | GSR (0.43) | GSRGNAI3GNAO1GNAI1OTC | |
| Glycine SCHEMBL7934640 | 0.92 | GSR (0.38) | GSRGNAI3GNAO1GNAI1OTC | |
| SCHEMBL301607 | 0.90 | GNAI3 (0.46) | GSRGNAI3GNAO1GNAI1OTC | |
| SCHEMBL11660913 | 0.90 | GNAI3 (0.46) | GSRGNAI3GNAO1GNAI1OTC | |
| SCHEMBL2899157 | 0.90 | OTC (0.43) | GSROTCDDAH1NPY4RNPY1R | |
| SCHEMBL2057401 | 0.88 | GNAI3 (0.44) | GSRGNAI3GNAO1GNAI1OTC | |
| Lysine SCHEMBL5579150 | 0.88 | GSR (0.49) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL1278143 | 0.88 | GSR (0.49) | GSRGNAI3GNAO1GNAI1OTC | |
| Lysine SCHEMBL16762313 | 0.87 | GSR (0.39) | GSRGNAI3GNAO1GNAI1OTC | |
| Glutamine SCHEMBL9393966 | 0.86 | GSR (0.42) | GSRGNAI3GNAO1GNAI1OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043987-A4 | USE OF SERINE PROTEASE INHIBITORS TO INHIBIT PATHOPHYSIOLOGY AND NEUROPATHOLOGY IN A HOST | THURIS CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030144212-A1 | USE OF SERINE PROTEASE INHIBITORS TO INHIBIT PATHOPHYSIOLOGY AND NEUROPATHOLOGY IN A HOST | THURIS CORPORATION | 2003-07-31 | — | — | US | disclosed |
| US-6486303-B1 | Method for making hormone heterodimers | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY | 2002-11-26 | — | — | US | disclosed |
| EP-1043987-A1 | USE OF SERINE PROTEASE INHIBITORS TO INHIBIT PATHOPHYSIOLOGY AND NEUROPATHOLOGY IN A HOST | Hoffman, Keith B. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999034789-A1 | USE OF SERINE PROTEASE INHIBITORS TO INHIBIT PATHOPHYSIOLOGY AND NEUROPATHOLOGY IN A HOST | HOFFMAN KEITH B (US) | 1999-07-15 | — | — | WO | disclosed |