SCHEMBL769420

SCHEMBL769420

N=C(N)NCCC[C@H](N)C(=O)OC(=O)[C@H](N)CCCN

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
GSR P00390 1/20 0.37
NPY4R P50391 7/20 0.36
NPY1R P25929 5/20 0.36
DPP7 Q9UHL4 3/20 0.36
NOS1 P29475 1/20 0.36
RRM1 P23921 1/20 0.36
OTC P00480 1/20 0.35
ALOX15 P16050 1/20 0.34
NPY2R P49146 4/20 0.34
NPY5R Q15761 4/20 0.34
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DDAH1 O94760 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301607 0.95 GNAI3 (0.46) GNAI3GNAO1GNAI1GSRNPY4R
SCHEMBL11660913 0.95 GNAI3 (0.46) GNAI3GNAO1GNAI1GSRNPY4R
SCHEMBL2057401 0.94 GNAI3 (0.44) GNAI3GNAO1GNAI1GSRNPY4R
SCHEMBL28712062 0.94 NPY4R (0.39) GNAI3GNAO1GNAI1NPY4RNPY1R
SCHEMBL9237239 0.94 NPY4R (0.39) GNAI3GNAO1GNAI1NPY4RNPY1R
SCHEMBL288133 0.94 NPY4R (0.39) GNAI3GNAO1GNAI1NPY4RNPY1R
Hydrochloric Acid SCHEMBL8039440 0.92 NPY4R (0.38) GNAI3GNAO1GNAI1NPY4RNPY1R
Hydrochloric Acid SCHEMBL8040222 0.92 NPY4R (0.38) GNAI3GNAO1GNAI1NPY4RNPY1R
SCHEMBL7543442 0.89 GSR (0.43) GNAI3GNAO1GNAI1GSRNPY4R
SCHEMBL27722340 0.89 NPY4R (0.37) GNAI3GNAO1GNAI1NPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948775-B1 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA US HEALTH (US) 2018-10-03 EP claimed
US-20150344969-A1 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-12-03 US claimed
EP-2948775-A2 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA The United States Of America,As Represented By The Secretary, Department Of Health & Human Services (US) 2015-12-02 EP claimed
WO-2014116833-A2 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2014-07-31 WO claimed
EP-0507872-B1 THE USE OF ARGININE AS AN IMMUNOSTIMULATOR BRAUN MEDICAL INC (US) 2000-04-26 EP claimed
WO-2026107124-A1 GRAPH NEURAL NETWORK-BASED SYSTEM FOR METABOLOMIC NETWORK ANALYSIS AND EMBRYO IMPLANTATION PREDICTION RHEA FERTILITY SINGAPORE PTE. LTD. (SG) 2026-05-21 WO disclosed
US-10328162-B1 CEST systems exhibiting a concentration independent responsiveness BRACCO IMAGING S.P.A. (IT) 2019-06-25 US disclosed
EP-2948775-B1 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA US HEALTH (US) 2018-10-03 EP disclosed
US-9518093-B2 Topical formulation of arginine-rich cyclic antimicrobial peptides NOVABIOTICS LIMITED (GB) 2016-12-13 US disclosed
US-20160168203-A1 Cyclic Antimicrobial Peptides NOVABIOTICS LIMITED (GB) 2016-06-16 US disclosed
US-20150344969-A1 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-12-03 US disclosed
EP-2948775-A2 COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA The United States Of America,As Represented By The Secretary, Department Of Health & Human Services (US) 2015-12-02 EP disclosed
US-4376825-A ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS SYVA COMPANY (US) 1983-03-15 US disclosed
US-4282325-A FOR AMPLIFICATION IN ASSAYS SYVA COMPANY (US) 1981-08-04 US disclosed
US-4203802-A ENZYME BOUND TO AN ESTROGEN LIGAND SYVA COMPANY (US) 1980-05-20 US disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4069214-A ACRYLIC ESTER POLYMER, AMINO ACID CURING AGENT, COATING METALS, BONDING PLYWOOD, FINISHING TEXTILES SANYO TRADING CO., LTD. (JA) 1978-01-17 US disclosed
US-4067774-A Compounds for enzyme amplification assay SYVA COMPANY (US) 1978-01-10 US disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10328162-B1 CEST systems exhibiting a concentration independent responsiveness NCS1, CERS2, LSS GNAI3 682/4885GNAO1 2430/4885GNAI1 1433/4885
US-20160168203-A1 Cyclic Antimicrobial Peptides VIP, FPR3, FPR1 GNAI3 2212/4885GNAO1 4669/4885GNAI1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.