Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487011 | 0.88 | ESR1 (0.54) | NPC1RAB9AMRGPRX4ESR1ESR2 | |
| SCHEMBL15967552 | 0.82 | HPGD (0.45) | NPC1RAB9AMRGPRX4ESR1ESR2 | |
| SCHEMBL13135118 | 0.81 | MTNR1B (0.57) | NPC1RAB9AESR1ESR2MEN1 | |
| SCHEMBL19320327 | 0.81 | RXRA (0.51) | — | |
| SCHEMBL287805 | 0.81 | CYP3A4 (0.63) | NPC1RAB9AESR1ESR2MEN1 | |
| SCHEMBL1788901 | 0.81 | POLB (0.47) | MRGPRX4ESR1ESR2MEN1KMT2A | |
| SCHEMBL1789018 | 0.81 | ELANE (0.51) | NPC1RAB9AMRGPRX4ESR1ESR2 | |
| SCHEMBL1787081 | 0.80 | HPGD (0.47) | MRGPRX4ESR1ESR2MEN1KMT2A | |
| SCHEMBL28452476 | 0.80 | CYP4F2 (0.46) | NPC1RAB9AMRGPRX4MEN1KMT2A | |
| SCHEMBL5199329 | 0.80 | HPGD (0.49) | NPC1RAB9AMRGPRX4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |