Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144315 | 0.87 | RAB9A (0.56) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL15384064 | 0.80 | SMN1; SMN2 (0.50) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7541114 | 0.80 | SMN1; SMN2 (0.50) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7540214 | 0.77 | SMN1; SMN2 (0.47) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7547525 | 0.77 | NPC1 (0.47) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5764963 | 0.75 | NPC1 (0.54) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL10749720 | 0.74 | NPC1 (0.53) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5766517 | 0.73 | RAB9A (0.51) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5766519 | 0.73 | RAB9A (0.51) | RAB9ANPC1HPGDSMN1; SMN2MAPT | |
| SCHEMBL11367779 | 0.72 | RAB9A (0.58) | RAB9ANPC1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860432-B1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | TAKASAGO PERFUMERY CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5859249-A | CYCLIZATION A 7-(N-SUBSTITUTED AMINO)-3-OXO-2-PHENYLHEPTANOATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5801271-A | CHEMICAL INTERMEDIATES FOR ANTIDEPRESSANTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0860432-A1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0860426-A1 | 7-(n-substituted amino)-2-phenylheptanoic acid derivative and process for manufacturing the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |