Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384064 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL7549282 | 0.87 | RAB9A (0.42) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL7549342 | 0.86 | CA1 (0.42) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL7774549 | 0.86 | RAB9A (0.42) | SMN1; SMN2NPC1HPGDRAB9AKMT2A | |
| SCHEMBL7540214 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL7547525 | 0.85 | NPC1 (0.47) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL1144315 | 0.83 | RAB9A (0.56) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL7543674 | 0.80 | RAB9A (0.54) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL11374162 | 0.75 | TSHR (0.57) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL5764963 | 0.72 | NPC1 (0.54) | SMN1; SMN2NPC1HPGDRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10279559-A | — | — | None | — | — | JP | disclosed |
| EP-0860432-B1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | TAKASAGO PERFUMERY CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0949247-B1 | Process for the preparation of piperidinylidene derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5859249-A | CYCLIZATION A 7-(N-SUBSTITUTED AMINO)-3-OXO-2-PHENYLHEPTANOATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| JP-H10279559-A | 2-PHENYL-2-(2'-PIPERIDINYLIDENE)ACETIC ACID ESTER DERIVATIVE AND ITS PRODUCTION | TAKASAGO INTERNATL CORP | 1998-10-20 | — | — | JP | disclosed |
| US-5801271-A | CHEMICAL INTERMEDIATES FOR ANTIDEPRESSANTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0860432-A1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0860426-A1 | 7-(n-substituted amino)-2-phenylheptanoic acid derivative and process for manufacturing the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |