Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541114 | 0.85 | SMN1; SMN2 (0.50) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL15384064 | 0.85 | SMN1; SMN2 (0.50) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7540214 | 0.81 | SMN1; SMN2 (0.47) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL1144315 | 0.79 | RAB9A (0.56) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7543674 | 0.77 | RAB9A (0.54) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL11375371 | 0.76 | TSHR (0.42) | NPC1RAB9ASMN1; SMN2KMT2ATSHR | |
| SCHEMBL7549282 | 0.72 | RAB9A (0.42) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7549342 | 0.71 | CA1 (0.42) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7774549 | 0.71 | RAB9A (0.42) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL5764963 | 0.69 | NPC1 (0.54) | NPC1RAB9AHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860432-B1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | TAKASAGO PERFUMERY CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5859249-A | CYCLIZATION A 7-(N-SUBSTITUTED AMINO)-3-OXO-2-PHENYLHEPTANOATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0860432-A1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |