SCHEMBL754371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13566072	0.81	LMNA (0.41)	FYNTRPA1HTR2CHTR2AKCNH2
	SCHEMBL754699	0.77	HTR2C (0.39)	FYNHTR2CHTR2AKCNH2GRK5
	SCHEMBL13563985	0.75	HTR2C (0.41)	FYNHTR2CHTR2AKCNH2CNR2
	SCHEMBL752920	0.74	MAOB (0.42)	FYNGRK5CNR2
	SCHEMBL5903167	0.73	CCR1 (0.39)	—
	SCHEMBL756391	0.73	HTR2C (0.41)	FYNGRM2TRPA1HTR2CHTR2A
	SCHEMBL361335	0.73	—	—
	SCHEMBL29426609	0.73	—	—
	SCHEMBL16431630	0.73	ESR1 (0.59)	METTAAR1
	SCHEMBL27588300	0.72	FYN (0.34)	FYNGRM2HTR2CHTR2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.