SCHEMBL752920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754612	0.79	MAOB (0.40)	MAOBALDH1A1NR4A2
	SCHEMBL5360275	0.77	ALDH1A1 (0.64)	MAOBALDH1A1MAOALMNAKDM4E
	SCHEMBL11387130	0.77	P4HTM (0.56)	ALDH1A1LMNAKDM4EMAPK1L3MBTL1
	SCHEMBL754255	0.77	CNR2 (0.34)	MAOBALDH1A1LMNAACACBCNR2
	SCHEMBL11016027	0.74	ALDH1A1 (0.52)	ALDH1A1CYP3A4
	SCHEMBL754371	0.74	FYN (0.43)	FYNGRK5CNR2
	SCHEMBL13566072	0.74	LMNA (0.41)	NPSR1LMNAFYNL3MBTL1
	SCHEMBL2933128	0.74	ALDH1A1 (0.41)	ALDH1A1LMNACYP3A4
	SCHEMBL13140958	0.73	ALDH1A1 (0.40)	ALDH1A1LMNACYP3A4
	SCHEMBL14420953	0.73	POLB (0.46)	ALDH1A1LMNACYP3A4MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.