Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543899 | 0.92 | MAPT (0.45) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL7547406 | 0.90 | KDR (0.46) | KDRCETPALOX5EPHX2KMT2A | |
| SCHEMBL7548871 | 0.87 | KDR (0.44) | KDRALOX5EPHX2KMT2AHTT | |
| SCHEMBL8666294 | 0.85 | SMN1; SMN2 (0.49) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL7545447 | 0.85 | MAPT (0.45) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL7541413 | 0.83 | LMNA (0.47) | MAPTKDM4EHPGDKDRALOX5 | |
| SCHEMBL7542502 | 0.82 | MAPT (0.46) | MAPTKDRCETPKMT2AMEN1 | |
| SCHEMBL7544894 | 0.82 | KDR (0.40) | KDRALOX5EPHX2KMT2AHTT | |
| SCHEMBL7543749 | 0.81 | ALOX5 (0.45) | MAPTHPGDKDRCETPALOX5 | |
| SCHEMBL7543761 | 0.80 | MAPT (0.46) | MAPTKDM4EHPGDCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |