Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937497 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL15798472 | 0.83 | NR4A2 (0.41) | ALDH1A1KDM4EGAAHPGDGABRA1 | |
| SCHEMBL23147548 | 0.76 | TDP1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29100443 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL28975325 | 0.75 | MAPT (0.50) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL6272160 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL4045529 | 0.72 | TSHR (0.61) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL1810204 | 0.72 | KMT2A (0.61) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL7439372 | 0.71 | KMT2A (0.61) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL7546356 | 0.71 | CYP1A2 (0.51) | ALDH1A1GAAHPGDKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |