Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864007 | 0.79 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL7545216 | 0.79 | TSHR (0.43) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL10866361 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL10864339 | 0.77 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL11652356 | 0.73 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL10598450 | 0.72 | KMT2A (0.47) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL7544489 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL7543900 | 0.71 | ALDH1A1 (0.49) | CYP1A2CYP2C19HPGDLMNAALDH1A1 | |
| SCHEMBL10595042 | 0.70 | KMT2A (0.45) | CYP1A2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL10597066 | 0.69 | KMT2A (0.44) | CYP1A2CYP2C9CYP2C19HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896043-B1 | Adhesive | TOKUYAMA CORP (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-6133338-A | TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF | TOKUYAMA CORPORATION (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0896043-A1 | Adhesive | TOKUYAMA CORPORATION (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |