SCHEMBL755553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2490161	0.91	BRD4 (0.43)	BRD4ABCB1PPARAANO1KDM5A
	SCHEMBL16921596	0.91	BRD4 (0.43)	BRD4ABCB1KMT2AANO1KDM5A
	SCHEMBL3432852	0.90	BRD4 (0.40)	BRD4ABCB1PPARAANO1KDM5A
	SCHEMBL756684	0.90	BRD4 (0.42)	BRD4MAPK14ABCB1ANO1KDM5A
	SCHEMBL753747	0.89	KDM5A (0.42)	BRD4ABCB1KMT2AKDM5AKDM5B
	SCHEMBL754597	0.86	BRD4 (0.39)	BRD4ABCB1KMT2AANO1KDM5A
	SCHEMBL753097	0.85	BRD4 (0.42)	BRD4MAPK14KMT2APPARAMAOB
	SCHEMBL754396	0.84	BRD4 (0.41)	BRD4MAPK14ABCB1KMT2AMAOB
	SCHEMBL752167	0.83	BRD4 (0.34)	BRD4MAPK14KMT2APPARAKDM5A
	SCHEMBL752441	0.79	BRD4 (0.40)	BRD4PPARAANO1KDM5AKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.