Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947640 | 0.83 | PLAU (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL194554 | 0.79 | PLAU (0.50) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL29358794 | 0.79 | PLAU (0.50) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL2852412 | 0.79 | PLAU (0.50) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL2418686 | 0.79 | CYP2A6 (0.50) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL251028 | 0.79 | PLAU (0.50) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL15940603 | 0.75 | ADORA2A (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| Hydrochloric Acid SCHEMBL8116929 | 0.73 | ADORA2A (0.53) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL2431412 | 0.73 | CYP2A6 (0.48) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL17370957 | 0.73 | CHAT (0.49) | PLAUCYP2A6F12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155454-A1 | CARBONIC ANHYDRASE IX-TARGETING RADIOACTIVE DIAGNOSTIC AND THERAPEUTIC MEDICAMENT AND METHOD FOR PREPARING SAME | 无锡诺宇医药科技有限公司 | 2023-08-24 | — | — | WO | disclosed |
| WO-2002043680-A1 | FIXATION OF CARBOHYDRATES TO FIBROUS MATERIALS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-06-06 | — | — | WO | disclosed |
| WO-2002043678-A2 | ENZYMATIC FIXATION OF DERIVATISED CARBOHYDRATES TO FIBROUS MATERIALS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-06-06 | — | — | WO | disclosed |