Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544337 | 1.00 | POLB (0.40) | POLBPKMKDM4EKMT2ALMNA | |
| SCHEMBL10323975 | 0.71 | MEN1 (0.54) | POLBKMT2ACMA1ALDH1A1GSK3B | |
| SCHEMBL22287862 | 0.70 | MMP1 (0.42) | KDM4EKMT2ACMA1ALDH1A1CYP3A4 | |
| SCHEMBL22287726 | 0.68 | TP53 (0.51) | KDM4EKMT2ALMNAALDH1A1HKDC1 | |
| SCHEMBL31404224 | 0.66 | CYP3A4 (0.40) | POLBKDM4ELMNACMA1CYP3A4 | |
| SCHEMBL21847080 | 0.66 | KDM4E (0.51) | KDM4EKMT2ALMNACMA1ALDH1A1 | |
| SCHEMBL25316050 | 0.65 | ALDH1A1 (0.43) | POLBPKMKDM4EKMT2AALDH1A1 | |
| SCHEMBL30714028 | 0.64 | GAA (0.49) | KDM4EKMT2ACMA1ALDH1A1CYP3A4 | |
| SCHEMBL430661 | 0.64 | CMA1 (0.66) | KDM4EKMT2ACMA1ALDH1A1GSK3A | |
| SCHEMBL25894467 | 0.64 | ALDH1A1 (0.42) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002045853-A1 | LEWIS ACID CATALYSIS USING CHIRAL METAL COMPLEXES | DOYLE MICHAEL P (US) | 2002-06-13 | — | — | WO | disclosed |