Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447368 | 0.79 | TSHR (0.42) | TSHRGAAPOLBGLAPDK2 | |
| SCHEMBL29350569 | 0.78 | TSHR (1.00) | TSHRGAAPOLBGLAPDK2 | |
| SCHEMBL17451259 | 0.78 | TSHR (1.00) | TSHRGAAPOLBGLAPDK2 | |
| SCHEMBL109685 | 0.78 | TSHR (1.00) | TSHRGAAPOLBGLAPDK2 | |
| SCHEMBL15547708 | 0.78 | KIF11 (0.47) | TSHRGAAPOLBGLANR1H2 | |
| SCHEMBL9904797 | 0.76 | TSHR (0.41) | TSHRGAAPOLBGLAPDK2 | |
| Hydrochloric Acid SCHEMBL8642589 | 0.76 | TSHR (0.95) | TSHRGAAPOLBGLAPDK2 | |
| Water SCHEMBL20506731 | 0.76 | TSHR (0.95) | TSHRGAAPOLBGLAPDK2 | |
| Ammonia Solution, Strong SCHEMBL6812982 | 0.76 | TSHR (0.95) | TSHRGAAPOLBGLAPDK2 | |
| SCHEMBL22589784 | 0.74 | TSHR (0.91) | TSHRGAAPOLBGLAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725284-B1 | Ocular lens material | MENICON CO LTD (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0634673-B1 | Ocular lens material | MENICON CO LTD (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5703143-A | SILICON-CONTAINING POLYPHENYLENE ETHER POLYMER | MENICON CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5605942-A | POLYIMIDE HAVING EXCELLENT TRANSPARENCY, OXYGEN PERMEABILITY, HEAT RESISTANCE, ULTRAVIOLET LIGHT ABSORPTION | MENICON CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0725284-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1996-08-07 | — | — | EP | disclosed |
| EP-0634673-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1995-01-18 | — | — | EP | disclosed |