SCHEMBL7544676

SCHEMBL7544676

C=C(C#N)C(=O)NCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 9/20 0.52
▸ ZDHHC20 Q5W0Z9 2/20 0.49
▸ ZDHHC2 Q9UIJ5 2/20 0.49
▸ PLA2G2A P14555 1/20 0.47
▸ CASP2 P42575 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ NAAA Q02083 1/20 0.44
▸ PLA2G4A P47712 1/20 0.44
▸ HPGD P15428 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ TP53 P04637 1/20 0.42
▸ HSP90AA1 P07900 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ MGLL Q99685 1/20 0.42
▸ DPP7 Q9UHL4 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7550565 1.00 EPHX1 (0.52) EPHX1ZDHHC20ZDHHC2PLA2G2ACASP2
SCHEMBL7546089 1.00 EPHX1 (0.52) EPHX1ZDHHC20ZDHHC2PLA2G2ACASP2
SCHEMBL7548924 1.00 EPHX1 (0.52) EPHX1ZDHHC20ZDHHC2PLA2G2ACASP2
SCHEMBL7550564 1.00 EPHX1 (0.52) EPHX1ZDHHC20ZDHHC2PLA2G2ACASP2
SCHEMBL7550275 0.98 EPHX1 (0.48) EPHX1ZDHHC20ZDHHC2PLA2G2ACASP2
SCHEMBL7542437 0.93 EPHX1 (0.44) EPHX1ZDHHC20ZDHHC2SMN1; SMN2HPGD
SCHEMBL7545856 0.88 EPHX2 (0.44) EPHX1ZDHHC20MGLLALDH1A1
SCHEMBL7550215 0.88 EPHX2 (0.44) EPHX1ZDHHC20MGLLALDH1A1
SCHEMBL7549085 0.88 EPHX2 (0.44) EPHX1ZDHHC20MGLLALDH1A1
SCHEMBL7550559 0.88 EPHX2 (0.44) EPHX1ZDHHC20MGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 — — US claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 — — EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 — — US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 — — EP claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 — — WO claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 — — US disclosed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 — — EP disclosed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 — — US disclosed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 — — EP disclosed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF EPHX1 2739/4885ZDHHC20 1099/4885ZDHHC2 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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